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Evidence for a p23 caspase-cleaved form of p27[KIP1] involved in G1 growth arrest

✍ Scribed by Loubat, Agnès; Rochet, Nathalie; Turchi, Laurent; Rezzonico, Roger; Far, Dariush Farahi; Auberger, Patrick; Rossi, Bernard; Ponzio, Gilles

Book ID: 110062101
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 339 KB
Volume: 18
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1202668

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## Abstract Butyrate, a non‐toxic short‐chain fatty acid (SCFA) and inhibitor of histone deacetylase (HDAC), has potential as an anti‐tumor agent because it imposes a reversible G~1~ block in normal cells yet induces apoptosis in tumor lines. As a potent reactivator of fetal globin transcription, b