The appearance of autoantibodies against mitochondria in patients with primary biliary cirrhosis has been known for more than 25 yr. In the past, based on the biochemical complexity of the mitochondrion and the use of crude extracts for immunodiagnosis, a degree of nonspecificity in assaying for ant
β¦ LIBER β¦
Evidence for a locally driven mucosal response and the presence of mitochondrial antigens in saliva in primary biliary cirrhosis
β Scribed by Sandra Reynoso-Paz; Patrick S.C. Leung; Judy Van de Water; Atsushi Tanaka; Santiago Munoz; Nathan Bass; Keith Lindor; Paul J. Donald; Ross L. Coppel; Aftab A. Ansari; M. Eric Gershwin
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 95 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0270-9139
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Some patients with autoimmune liver disease present with a clinical and/or histological picture showing characteristic findings of both autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). Various names, mostly overlap syndrome, have been used to describe these cases, which have thus far