Evidence for a link betweenTNFRSF11Aand risk of breast cancer
✍ Scribed by Núria Bonifaci; Marta Palafox; Pasquale Pellegrini; Ana Osorio; Javier Benítez; Paolo Peterlongo; Siranoush Manoukian; Bernard Peissel; Daniela Zaffaroni; Gaia Roversi; Monica Barile; Alessandra Viel; Frederique Mariette; Loris Bernard; Paolo Radice; Bella Kaufman; Yael Laitman; Roni Milgrom; Eitan Friedman; María E. Sáez; Fina Climent; María Teresa Soler; Orland Diez; Judith Balmaña; Adriana Lasa; Teresa Ramón y Cajal; María-Dolores Miramar; Miguel de la Hoya; Pedro Pérez-Segura; Trinidad Caldés; Víctor Moreno; Ander Urruticoechea; Joan Brunet; Conxi Lázaro; Ignacio Blanco; Miguel Angel Pujana; Eva González-Suárez
- Publisher
- Springer US
- Year
- 2011
- Tongue
- English
- Weight
- 334 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0167-6806
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## Abstract Estrogens can become endogenous carcinogens __via__ formation of catechol estrogen quinones, which react with DNA to form specific depurinating estrogen‐DNA adducts. The mutations resulting from these adducts can lead to cell transformation and the initiation of breast cancer. Estrogen