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Evidence for a direct role of intracellular calcium in paracetamol toxicity

โœ Scribed by Alan R. Boobis; Caroline E. Seddon; Pari Nasseri-Sina; Donald S. Davies


Book ID
115781315
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
667 KB
Volume
39
Category
Article
ISSN
0006-2952

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In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated calcium currents nor for changes of the intracellu