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Evidence by Chemical Modification for the Involvement of One or More Tryptophanyl Residues of Bovine Antithrombin in the Binding of High-Affinity Heparin

✍ Scribed by Ingemar BJÖRK; Kerstin NORDLING


Book ID
115118119
Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
625 KB
Volume
102
Category
Article
ISSN
1432-1327

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Scatchard analysis of binding of 125I-basic fibroblast growth factor (FGF) to baby hamster kidney (BHK) cells revealed the presence of two binding sites: a high affinity site with KD of 20 pM and 80,000 sites per cell and a low affinity site with KD of about 2 nM and 600,000 sites per cell. The bind