## Abstract The vitamin D receptor (VDR) may importantly modulate risk of colorectal cancer either independently or in conjunction with calcium and vitamin D intake. We evaluate the association between calcium, vitamin D, dairy products, and __VDR__ polymorphisms in 2 caseโcontrol studies of colon
Evidence-based policy on dietary calcium and vitamin D
โ Scribed by Ian R Reid; Alison Avenell
- Publisher
- American Society for Bone and Mineral Research
- Year
- 2011
- Tongue
- English
- Weight
- 55 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0884-0431
- DOI
- 10.1002/jbmr.327
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
The Institute of Medicine's report on calcium and vitamin D makes a positive contribution by grounding its recommendations on the available evidence base. The committee does not substantially change recommended dietary intakes for calcium and modestly increases those for vitamin D based on the need for a median serum 25โhydroxyvitamin D of 40โnmol/L. They do not support the suggestion that all adults should have levels >75โnmol/L. The committee concludes that current evidence does not support nonskeletal benefits for vitamin D or calcium, and notes that higher intakes of both could have adverse health consequences. The present authors are generally in agreement with these conclusions, with some caveats regarding the evidence base used. However, we believe that the central role of sunlight exposure in determining vitamin D status needs to be explicitly reflected in public policy in this area. ยฉ 2011 American Society for Bone and Mineral Research.
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