Evidence against the functional involvement of outwardly rectifying Cl− channels in agonist-induced mast cell exocytosis

The outwardly rectifying Cl−channel is n

The outwardly rectifying Cl−channel is not involved in cAMP-mediated Cl−secretion in HT-29 cells: evidence for a very-low-conductance Cl−channel

✍ Horst Fischer; Klaus -M. Kreusel; Beate Illek; Terry E. Machen; Ulrich Hegel; Wo 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 990 KB

The patch-clamp technique and transepithelial current measurements in conjunction with analysis of transepithelial current noise were employed in order to clarify the role of the outwardly rectifying, depolarization-induced C1-channel (ORDIC) during cAMP-mediated C1-secretion in HT-29/B6 cells. Conf