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Evidence against association of the FE65 gene (APBB1) intron 13 polymorphism in Alzheimer's patients

✍ Scribed by Suzanne Y Guénette; Lars Bertram; Adam Crystal; Benjamin Bakondi; Bradley T Hyman; G.William Rebeck; Rudolph E Tanzi; Deborah Blacker

Book ID
117471256
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
84 KB
Volume
296
Category
Article
ISSN
0304-3940

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Association of a polymorphism in intron 13 of the monoamine oxidase B gene with Parkinson disease
✍ Costa, Paola; Checkoway, Harvey; Levy, Drew; Smith-Weller, Terri; Franklin, Gary 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB 👁 3 views

## Monoamine oxidase B (MAO -B ) is an enzyme that has relevance for Parkinson disease (PD) because of its roles in catabolizing dopamine and potentially activating exogenous neurotoxicants. A polymorphism of the gene encoding MAO-B has been identified as a single base change (A or G) in intron