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Everolimus for Advanced Pancreatic Neuroendocrine Tumors

✍ Scribed by Yao, James C.; Shah, Manisha H.; Ito, Tetsuhide; Bohas, Catherine Lombard; Wolin, Edward M.; Van Cutsem, Eric; Hobday, Timothy J.; Okusaka, Takuji; Capdevila, Jaume; de Vries, Elisabeth G.E.; Tomassetti, Paola; Pavel, Marianne E.; Hoosen, Sakina; Haas, Tomas; Lincy, Jeremie; Lebwohl, David; Öberg, Kjell

Book ID
121461164
Publisher
Massachusetts Medical Society
Year
2011
Tongue
English
Weight
667 KB
Volume
364
Category
Article
ISSN
0096-6762

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Everolimus for Advanced Pancreatic Neuro
Everolimus for Advanced Pancreatic Neuroendocrine Tumors
✍ Yao, James C.; Shah, Manisha H.; Ito, Tetsuhide; Bohas, Catherine Lombard; Wolin 📂 Article 📅 2011 🏛 Massachusetts Medical Society 🌐 English ⚖ 667 KB

## Background: Everolimus, an oral inhibitor of mammalian target of rapamycin (mtor), has shown antitumor activity in patients with advanced pancreatic neuroendocrine tumors, in two phase 2 studies. we evaluated the agent in a prospective, randomized, phase 3 study. ## Methods: We randomly assign