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Evaluation of11C-methionine PET as a surrogate endpoint after treatment of grade 2 gliomas

✍ Scribed by Dan Ribom; Marjoleine Schoenmaekers; Henry Engler; Anja Smits

Publisher
Springer US
Year
2005
Tongue
English
Weight
262 KB
Volume
71
Category
Article
ISSN
0167-594X

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## Abstract 2‐Fluoronorapomorphine, the PET labelling precursor to 2‐fluoro‐__N__‐[^11^C]propylnorapomorphine, was prepared in 13 steps from codeine in a total yield of 10 %. Codeine was converted in four steps into __N__‐benzylnorcodeine which was oxidised by using the Swern protocol. Subsequent a