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Evaluation of Valproic Acid (VPA) Developmental Toxicity and Pharmacokinetics in Sprague—Dawley Rats

✍ Scribed by BINKERD, P. E.; ROWLAND, J. M.; NAU, H.; HENDRICKX, A. G.

Book ID
125835932
Publisher
Oxford University Press
Year
1988
Tongue
English
Weight
565 KB
Volume
11
Category
Article
ISSN
1096-6080

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## Abstract The developmental toxicity potential of butylparaben (CAS No. 94‐26‐8) was evaluated in rats. Sprague‐Dawley rats were administered butylparaben in 0.5% carboxymethylcellulose by oral gavage at dose levels of 0, 10, 100, or 1,000 mg/kg/day on gestation days (GD) 6–19 (sperm positive day