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Evaluation of Using Dog as an Animal Model to Study the Fraction of Oral Dose Absorbed of 43 Drugs in Humans

โœ Scribed by Win L. Chiou; Hyun Y. Jeong; Sang M. Chung; Ta C. Wu


Book ID
110251478
Publisher
Springer US
Year
2000
Tongue
English
Weight
173 KB
Volume
17
Category
Article
ISSN
0724-8741

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Pigs were given large oral doses of paracetamol, amylobarbitone and amitriptyline. The effect of administering activated charcoal at varying intervals after dosing on the blood drug-level profiles of paracetamol and amylobarbitone was assessed by comparison with the profiles obtained when charcoal t