✦ LIBER ✦

Evaluation of the V79 cell metabolic co-operation assay as a screen in vitro for developmental toxicants

✍ Scribed by Toraason, M.; Bohrman, J.S.; Krieg, E.; Combes, R.D.; Willington, S.E.; Zajac, W.; Langenbach, R.

Book ID: 122100799
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 827 KB
Volume: 6
Category: Article
ISSN: 0887-2333
DOI: 10.1016/0887-2333(92)90011-F

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Forward mutation assay of V79 cells to 6

Forward mutation assay of V79 cells to 6-thioguanine resistance in a soft agar technique that eliminates effects of metabolic co-operation

✍ Yoshisuke Nishi; Makiko M. Hasegawa; Naomichi Inui 📂 Article 📅 1984 🏛 Elsevier Science 🌐 English ⚖ 675 KB

Evaluation of a new procedure for the fl

Evaluation of a new procedure for the flow cytometric analysis of in vitro, chemically induced micronuclei in V79 cells

✍ Danielle Roman; Franziska Locher; Willi Suter; André Cordier; Maria Bobadilla 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB 👁 2 views

Measurement of the frequency of micronuclei induced in cells by ionizing radiation or by chemical treatment is widely used to analyze cytogenetic damage. The microscopic scoring of micronuclei is a tedious and time-consuming procedure. Therefore, attempts have been made to automate micronuclei scori

Preliminary evaluation of in vitro presc

Preliminary evaluation of in vitro prescreen assays for developmental toxicants based on cultured murine preimplantation embryos and a cell line developed from a bovine preimplantation embryo

✍ B.W. Kemppainen; P. Terse; O. Zurovac; D. Stringfellow 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 964 KB

In vitro short-term testing systems as p

In vitro short-term testing systems as prescreens for potential carcinogens: Simultaneous detection of sister chromatid exchanges and mutation response in a cell-mediated assay with V79 cells

✍ Nayak, B.N.; Héroux-Metcalf, C.; Rogers, C.G. 📂 Article 📅 1985 🏛 Elsevier Science 🌐 English ⚖ 639 KB

Evaluation of gap junctional intercellul

Evaluation of gap junctional intercellular communication using Chinese hamster V79 cells in a metabolic cooperation assay for prediction of carcinogenicity using U.S. NTP compounds, II: Application of a metabolic activation system

✍ S. Tanaka; Y. Iwase; Y. Takeda; K. Yoshikawa 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 91 KB

Acute and Chronic Toxicity of Veratrum V

Acute and Chronic Toxicity of Veratrum Viride††The Veratrum viride studied was the whole-powdered drug marketed by Irwin, Neisler & Co. under the name, Vertavis. The work reported herein was supported by a grant from this firm. The batch of powder used in these experiments was stated by the manufacturer to have been assayed biologically by the Craw method on Daphnia magna. One Craw unit of the material studied was stated to be 15.6mg. With regard to this assay, Mr. R. O. Craw has been so kind as to allow us to publish a brief explanation: A reference lot of Yerolrum oirid; powder was set-aside as a standard and a 10% w/v aqueous extract was made of this powder. The average median length of life in 50 assays of 1000 daphnia on immersion in the solution was determined to be 2.22 hours. The daphnia were considered dead when the heart was found to be in systolic standstill on microscopic examination. Succeeding lots of powder were assayed and their potency determined by relating the median length of life of daphnia to 2.22 hours, which is one unit. Twenty assays of 10 animals each were used on each lot of powder.‡‡The authors wish to thank Dr. J. F. A.,McManus of the Department of Pathology for a pathologic report on the tissues, and Mr. James Thomas and Mrs. Bobby E. Teague for technical assistance.

✍ Perdue, Adoline S. ;Bell, Frances ;Starnes, W.R. ;Hitchcock, Philip ;Teague, R.S 📂 Article 📅 1950 🏛 Elsevier ⚖ 346 KB 👁 2 views