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Evaluation of the stability and immunogenicity of autoclaved and nonautoclaved preparations of a vaccine against American tegumentary leishmaniasis

✍ Scribed by Paula M De Luca; Wilson Mayrink; Carlos Roberto Alves; Sergio G Coutinho; Marcia P Oliveira; Alvaro L Bertho; Vicente P Toledo; Carlos Alberto Costa; Odair Genaro; Sergio C.F Mendonça

Book ID
117433119
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
212 KB
Volume
17
Category
Article
ISSN
0264-410X

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✍ Ivan Dario Vélez; Sonia del Pilar Agudelo; Maria Patricia Arbelaez; Katherine Gi 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 699 KB

The safety and immunogenicity of an intramuscular (i.m.) and intradermal (ID) formulation of autoclaved Leishmania (Leishmania) amazonensis vaccine was evaluated in 296 volunteers in a randomized, placebo-controlled, double-blind trial in Colombia. There were 4 vaccination groups: i.m. vaccine, i.m.