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Evaluation of the potential toxicity of dibromoacetonitrile-induced apoptosis and tumor-initiating activity in rat liver

✍ Scribed by Naglaa Assaf; Neveen A. Salem; Wagdy K.B. Khalil; Hanaa H. Ahmed

Book ID
116463995
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
627 KB
Volume
49
Category
Article
ISSN
0278-6915

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## Abstract The haloacetonitrile, dibromoacetonitrile (DBAN), is a direct‐acting genotoxic agent that has been detected in drinking water. In a time course study, male Sprague‐Dawley rats were treated with DBAN (75 mg/kg PO), and killed at 0.5, 1, 2, and 4 hr after treatment. In a dose response stu