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Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid, ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy

โœ Scribed by Shingen Misaka; Souhei Kurosawa; Shinya Uchida; Akira Yoshida; Yoshihisa Kato; Yoshiyuki Kagawa; Shizuo Yamada

Book ID
118111428
Publisher
Pharmaceutical Press
Year
2010
Tongue
English
Weight
286 KB
Volume
63
Category
Article
ISSN
2042-7158

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๐Ÿ“œ SIMILAR VOLUMES

In vivo benzodiazepine receptor occupanc
In vivo benzodiazepine receptor occupancy by CL 218,872 visualized by positron emission tomography in the brain of the living baboon: modulation by GABAergic transmission and relation with anticonvulsant activity
โœ V. Sayette; C. Chavoix; E. Brouillet; P. Hantraye; M. Kunimoto; M. Khalili-Varas ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 611 KB

In vivo benzodiazepine receptor occupancy by increasing doses of CL 218,872 has been evaluated in the baboon Papio papio, using (11C) RO 15-1788 as specific radioligand and positron emission tomography as external detection system. Although BZR heterogeneity has been previously demonstrated in the b