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Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis

✍ Scribed by Yoony YJ Gent, Karin Weijers, Carla FM Molthoff…


Book ID
120705245
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
496 KB
Volume
15
Category
Article
ISSN
1478-6354

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## Abstract ## Objective To determine the expression of folate receptor β (FRβ) in synovial biopsy tissues and peripheral blood lymphocytes from rheumatoid arthritis (RA) patients and to identify novel folate antagonists that are more selective in the targeting and internalization of FRβ than meth