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Evaluation of the “micronucleus test” in comparison with chromosome studies on germ cells and on somatic cells of Chinese hamsters treated with cyclophosphamide

✍ Scribed by R. Hess; M. Langauer; R. Rathenberg; F. Strasser; D. Müller


Book ID
113253967
Publisher
Elsevier Science
Year
1973
Weight
74 KB
Volume
21
Category
Article
ISSN
0165-7992

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The potentiating effect of caffeine (1,3,7-trimethylxanthine) on chemically induced chromosome aberrations was studied in bone marrow cells of chinese hamsters, exposed to the alkylating agent cyclophosphamide. Four experimental series were performed: In the first two tests caffeine (200 mg/kg) or c