Avoparcin is a macrocyclic glycopeptide antibiotic structurally related to vancomycin, teicoplanin, and ristocetin A. When attached to 5-microns spherical silica gel, the avoparcin proved to be an effective chiral stationary phase (CSP) that could be used in the reversed-phase, normal-phase, and pol
Evaluation of the macrocyclic antibiotic vancomycin as a chiral selector for capillary electrophoresis
β Scribed by Dr. Daniel W. Armstrong; Kimber L. Rundlett; Jing-Ran Chen
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 809 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0899-0042
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## Abstract The glycopeptide antibiotic balhimycin and its haloanalogue bromobalhimycin were evaluated as chiral selectors for enantioresolution by capillary electrophoresis. In order (i) to eliminate the adsorption of the glycopeptide antibiotics on the capillary wall, (ii) to shorten the separati