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Evaluation of the introduction of the national Down syndrome screening program in the Netherlands: age-related uptake of prenatal screening and invasive diagnostic testing

✍ Scribed by Engels, Melanie A.J.; Bhola, Shama L.; Twisk, Jos W.R.; Blankenstein, Marinus A.; van Vugt, John M.G.


Book ID
122241032
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
319 KB
Volume
174
Category
Article
ISSN
0301-2115

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Maternal serum screening for Down syndrome involves biochemical tests such as alpha-fetoprotein ( FP), human chorionic gonadotrophin (hCG) and unconjugated oestriol (uE 3 ), either alone or in combination, that have variable detection and false-positive rates. Choosing a screening protocol requires