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Evaluation of the interaction between sitagliptin and cyclodextrin derivatives by capillary electrophoresis and nuclear magnetic resonance spectroscopy

✍ Scribed by Tamás Sohajda; Wen Hui Hu; Li Li Zeng; Hong Li; Lajos Szente; Béla Noszál; Szabolcs Béni


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
233 KB
Volume
32
Category
Article
ISSN
0173-0835

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## Abstract The possible mechanisms for the chiral recognition of 2‐(__R__)‐__N__‐[1‐(6‐aminopyridin‐2‐ylmethyl)piperidin‐4‐yl]‐2‐[(1__R__)‐3,3‐difluorocyclopentyl]‐2‐hydroxy‐2‐phenylacetamide (RR‐M3), and its enantiomer (SS‐M3) with octakis(2,3‐di‐__O__‐acetyl‐6‐sulfo)‐γ‐cyclodextrin (ODAS‐γ‐CD) a