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Evaluation of the immunosensitizing potential of chlorogenic acid using a popliteal lymph node assay in BALB/c mice

✍ Scribed by Zhaohua Liu; Zhaoping Liu; Yanqiu Shi; Gengyin Zhou


Book ID
116463214
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
389 KB
Volume
48
Category
Article
ISSN
0278-6915

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The murine local lymph node assay (LLNA) is currently recognized as a stand-alone test method for determining the skin sensitizing potential of chemicals. It has been incorporated into the official test guidelines published by some authorities, including the OECD. To avoid the use of radioisotopes,