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Evaluation of the immunocompetence of patients with transitional cell carcinoma of the bladder

✍ Scribed by Adolphs, H.-D. ;Steffens, L.

Publisher: Springer
Year: 1977
Tongue: English
Weight: 411 KB
Volume: 5
Category: Article
ISSN: 0300-5623
DOI: 10.1007/bf00257113

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✦ Synopsis

The cellular immunocompetence was examined by means of the quantitative DNCB hypersensitivity reaction in 152 patients with transitional cell carcinomas of the bladder of Broders grades 1-4. Against a control group of 367 normal controls of both sexes, 85 patients with transitional cell carcinomas of grades 1 and 2 showed a normal DNCB reactivity, irrespective of the frequency of tumour recurrence. In 9 patients of this group, an increase of malignancy from grade 2 to grade 3 was observed; the simultaneous deterioration of immunocompetence, however, was not statistically significant. On the other hand, with transitional cell carcinomas of grades 3 and 4, significant impairment of immunocompetence correlating with the tumour stage was noted.

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