Evaluation of the Efficiency of the Chiral Quaternary Ammonium Salt β-Np-NAS-Br in the Organic-Aqueous Phase-Transfer Alkylation of a Protected Glycine Derivative.

Evaluation of the Efficiency of the Chir

Evaluation of the Efficiency of the Chiral Quaternary Ammonium Salt β-Np-NAS-Br in the Organic-Aqueous Phase-Transfer Alkylation of a Protected Glycine Derivative

✍ Takashi Ooi; Yukitaka Uematsu; Keiji Maruoka 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 64 KB

The inherent efficiency of the N-spiro C 2symmetric chiral quaternary ammonium salt (S,S)-3 [(S,S)-b-Np-NAS-Br] has been evaluated in the representative organic-aqueous liquid-liquid phase-transfer benzylation and allylation of glycine tert-butyl ester benzophenone Schiff base (1). This revealed the