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Evaluation of the effect of pyrimethamine, an anti-malarial drug, on HIV-1 replication

✍ Scribed by Raphael M. Oguariri; Joseph W. Adelsberger; Michael W. Baseler; Tomozumi Imamichi

Book ID: 116968480
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 716 KB
Volume: 153
Category: Article
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2010.08.018

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Pyrimethamine is an antimalarial drug and a known teratogenic agent. With this drug, positive and negative results have been reported by various investigators in in vivo and in vitro genotoxicity/mutagenicity assays. In this investigation the genotoxic effects of pyrimethamine (PY) were tested in mi

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