Evaluation of the Developmental Toxicities of Coumarin, 4-Hydroxycoumarin, and 7-Hydroxycoumarin Using Fetax
β Scribed by Fort, Douglas J.; Stover, Enos L.; Propst, Timothy; Hull, Mendi A.; Bantle, John A.
- Book ID
- 120015862
- Publisher
- Informa plc
- Year
- 1998
- Tongue
- English
- Weight
- 604 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0148-0545
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Part 1, see [la]. ## ' ) ') For a recent review on the application of this reaction to the synthesis of natural products, see [2]. The formation of an acetophenone and an unidentified product from the reaction of cinnamaldehyde and 4-hydroxycoumarin has also been reported [7]. HELVETICA CHIMICA A
The developmental toxicity of thalidomide was evaluated using FETAX (Frog Embryo Teratogenesis Assay - Xenopus). Young X. Laevis embryos were exposed to this compound in each of two concentration-response experiments with and without differently induced exogenous metabolic activation systems (MASs)