Evaluation of a selectively oncolytic ad
Evaluation of a selectively oncolytic adenovirus for local and systemic treatment of cervical cancer
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Gerd J. Bauerschmitz; Anna Kanerva; Minghui Wang; Isabell Herrmann; Denise R. Sh
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Article
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2004
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John Wiley and Sons
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French
β 192 KB
## Abstract Treatment options for disseminated cervical cancer remain inadequate. Here, we investigated a strategy featuring Ad5βΞ24RGD, an oncolytic adenovirus replicationβcompetent selectively in cells defective in the __Rbβp16__ pathway, such as most cervical cancer cells. The viral fiber contai