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Evaluation of skin irritation of percutaneous absorption promoters by means of fractal dimension of rat skin structure

โœ Scribed by Jiro Akimoto; Kozo Takayama; Koichi Isowa; Tsuneji Nagai

Book ID
113368240
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
715 KB
Volume
128
Category
Article
ISSN
0378-5173

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Evaluation of skin damage caused by percutaneous absorption enhancers using fractal analysis
โœ Yasuko Obata; Takahiro Sesumi; Kozo Takayama; Koichi Isowa; Sharon Grosh; Steve ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 158 KB ๐Ÿ‘ 1 views

Fractal analysis of the cross-sectional morphology of rat skin was conducted to evaluate pathologic changes evoked by percutaneous absorption enhancers. Male hairless rats (WBN/Ht-ILA), 8 weeks old, weighing 160 to 180 g were used. Under anesthetization, glass cells (10-mm inner diameter) were attac