𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Evaluation of screening strategy for detecting hereditary nonpolyposis colorectal carcinoma

✍ Scribed by Taiji Furukawa; Fumio Konishi; Kazuhisa Shitoh; Masayuki Kojima; Hideo Nagai; Toshihiko Tsukamoto


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
98 KB
Volume
94
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


A cost-effectiveness analysis of colorec
✍ Hans F.Β A. Vasen; Marjolein van Ballegooijen; Eric Buskens; Jan K. Kleibeuker; B πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 92 KB πŸ‘ 2 views

## Background: It has been estimated that the prevalence of carriers of a mutated mismatch repair (mmr) gene among the general population in western countries is between 5 and 50 per 10,000. these carriers have a risk of >85% of developing colorectal carcinoma (crc) and therefore need careful follo

Evaluation of enzymatic mutation detecti
✍ Robyn Otway; Natasha Tetlow; June Hornby; Maija Kohonen-Corish πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 242 KB πŸ‘ 2 views

In hereditary nonpolyposis colorectal cancer (HNPCC), the majority of reported mutations are dispersed throughout the 35 exons of the two principal susceptibility genes, MLH1 and MSH2, and because of this complexity, rapid mutation screening methods are required. The aim of this study was to evaluat

Antibody-based screening for hereditary
✍ Mariann Christensen; Niels Katballe; Friedrik Wikman; Hanne Primdahl; Flemming B πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 577 KB

## Background: Germline mutations in the dna mismatch repair genes, msh2, mlh1, and others are associated with hereditary nonpolyposis colorectal cancer (hnpcc). due to the high costs of sequencing, cheaper screening methods are needed to identify hnpcc cases. ideally, these methods should have a h

Screening and preventive behaviors one y
✍ Veronica Collins; Bettina Meiser; Clara Gaff; D. James B. St. John; Jane Hallida πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 103 KB

## Abstract ## BACKGROUND Prevention benefits from predictive genetic testing for cancer will only be fully realized if appropriate screening is adopted after testing. The current study assessed screening and preventive behaviors during 12 months after predictive genetic testing for hereditary non

Comparison of selection strategies for g
✍ Carolina M. Reyes; Brian A. Allen; Jonathan P. Terdiman; Leslie S. Wilson πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 273 KB πŸ‘ 2 views

## Background: Molecular testing for hereditary nonpolyposis colorectal carcinoma (hnpcc) is becoming standard care and it is cost-effective compared with no genetic testing. however, the best strategy for detection of hnpcc gene carriers is unknown. ## Methods: We use a decision analytic model t