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Evaluation of retinoblastoma protein expression in asymptomatic and symptomatic Alzheimer's disease and normal elderly subjects

✍ Scribed by Silva, Aderbal; Grinberg, Lea; Farfel, Jose; Ferretti, Renata; Rocha, Rafael; Begnami, Maria; Brentani, Helena


Book ID
123224710
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
230 KB
Volume
7
Category
Article
ISSN
1552-5260

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## Abstract It was previously shown that herpes simplex virus type 1 (HSV1) DNA resides latently in a high proportion of aged brains and that in carriers of the type 4 allele of the apolipoprotein E gene (APOE‐Ρ4), it confers a strong risk of Alzheimer's disease. It was suggested that initial entry