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Evaluation of Primary Human Liver Cells in Bioreactor Cultures for Extracorporeal Liver Support on the Basis of Urea Production

✍ Scribed by Gesine Pless; Ingo Steffen; Katrin Zeilinger; Igor M. Sauer; Ekaterina Katenz; Daniel C. Kehr; Stephan Roth; Tim Mieder; Ruth Schwartlander; Christian Müller; Brigitte Wegner; Mariah S. Hout; Jörg C. Gerlach

Book ID
109093116
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
234 KB
Volume
30
Category
Article
ISSN
0160-564X

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## Abstract Cultivation of primary human liver cells in innovative 3D perfusion multi‐compartment capillary membrane bioreactors using decentralized mass exchange and integral oxygenation provides in vitro conditions close to the physiologic environment in vivo. While a few scale‐up bioreactors wer