Twin studies have played an important role in attempts to unravel the genetic contribution to diseases with adult onset, but have not been extensively utilized in efforts to establish the genetic contribution to common congenital anomalies. The paucity of twin research on congenital anomalies is par
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Evaluation of prenatal diagnosis of cleft lip with or without cleft palate and cleft palate by ultrasound: experience from 20 European registries
โ Scribed by Maurizio Clementi; Romano Tenconi; Fabrizio Bianchi; Claude Stoll
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 61 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0197-3851
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Cleft lip with or without cleft palate (CL +/- P) is the most frequent craniofacial malformation in different human populations and its cause is largely unknown. Several studies based on population associations have suggested that an allele mapping in the transforming growth factor alpha locus could