Evaluation of prednisolone and vincristine with and without L-asparaginase in acute lymphatic leukemia of childhood
β Scribed by V. P. Choudhry; R. K. Marwaha; D. P. Goyal; A. K. Sarya
- Book ID
- 112952832
- Publisher
- Springer-Verlag
- Year
- 1983
- Tongue
- English
- Weight
- 260 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0019-5456
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## Abstract Eleven patients with acute lymphocytic leukemia in relapse were treated with Lβasparaginase and cytosine arabinoside (1βΞ²βDβarabinofuranosylcytosine) in induction therapy and the same drugs plus cyclophosphamide in maintenance therapy. Three patients had complete remissions lasting 6, 1
A remission-induction regimen for childhood leukemia using cyclophosphamide, asparaginase, vincristine, and prednisone (CAVP) was compared to standard vincristine-prednisone (VP) induction. The more intensive regimen was associated with a lower complete remission rate (81% vs 93%) and a higher early