Evaluation of platelet-rich plasma and hydrostatic pressure regarding cell differentiation in nucleus pulposus tissue engineering

Tissue-engineered intervertebral disc an

Tissue-engineered intervertebral disc and chondrogenesis using human nucleus pulposus regulated through TGF-β1 in platelet-rich plasma

✍ Wei-Hong Chen; Wen-Cheng Lo; Jie-Jen Lee; Ching-Hua Su; Che-Tong Lin; Hen-Yu Liu 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 466 KB

## Abstract Human intervertebral disc (IVD) degeneration often initiated from the human nucleus pulposus (hNP) with aging leading to IVD destruction and extracellular matrix (ECM) depletion. Previously, we have successfully employed transforming growth factor‐β1 (TGF‐β1) to promote chondrogenesis o