Evaluation of phrenic nerve involvement and respiratory activity in Charcot-Marie-Tooth disease (HMSN type I)
β Scribed by F. Sartucci; L. Sagliocco; E. Busoni; M. Pistolesi; L. Murri
- Book ID
- 115870773
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 172 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0013-4694
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π SIMILAR VOLUMES
Peripheral myelin protein-22 (PMP22) is expressed in myelinating Schwann cells and shows significant homology to murine growth arrest-specific gene gas3. Charcot-Marie-Tooth disease type l a (CMTla) is a common hereditary demyelinating neuropathy. Recently it was demonstrated that the gene for PMP22
## Abstract Expression profiling was performed on sciatic nerve of normal mice and of transgenic mice overexpressing the peripheral myelin protein 22 kDa (PMP22). These mice represent a model for the hereditary peripheral neuropathy CharcotβMarie Tooth type 1A. Comparison of the profiles reveals th