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Evaluation of patients with chest pain and nondiagnostic ECG using thallium-201 myocardial planar imaging and technetium-99m first-pass radionuclide angiography in the emergency department

✍ Scribed by Philip L Henneman; Ismael G Mena; Robert J Rothstein; Karen B Garrett; Arnulfo S Pleyto; William J French


Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
526 KB
Volume
21
Category
Article
ISSN
1097-6760

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✦ Synopsis


Study objective:

The purpose of this study was to determine if thallium-201 myocardial planar imaging and technetium-99m first-pass radienuclide angiography, performed in the emergency department, could predict which patients with acute chest pain and nondiagnostic ECGs were more likely to have an acute myocardial infarction (AMI).

Design: Retrospective analysis.

Setting: Urban, county ED.

Type of participants: Convenience sample of 47 patients with acute chest pain suggestive of myocardial ischemia and nondiagnostic ECG.

Interventions: Thallium-201 myocardial imaging and technetium-99m first-pass radionuclide angiography in the ED.

Measurements and main results: Four patients had an AMI (ie, CK-MB _> 6% total CK). The combined scans had a sensitivity of 75%, (95% confidence interval [Oil,, a specificity of 42% (95% CI, 27-58%), an accuracy of 45% (95% CI, 19-99%), a positive predictive value of 11% (95% CI, 2-29%), and a negative predictive value of 95% (95% Cl, 75-100%)in predicting AMI.

Conclusion: Thallium-201 myocardial planar imaging and technetium-99m first-pass radionuclide angiography performed in the ED do not appear to be useful in determining which patients with acute chest pain and nondiagnostic ECG are likely to have an AMI.