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Evaluation of O-POSSUM in predicting in-hospital mortality after resection for oesophageal cancer

✍ Scribed by S. M. Lagarde; A. K. D. Maris; S. M. M. de Castro; O. R. C. Busch; H. Obertop; J. J. B. van Lanschot


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
110 KB
Volume
94
Category
Article
ISSN
0007-1323

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✦ Synopsis


Abstract

Background

The aims of the present study were to validate the Physiological and Operative Severity Score for the enUmeration of Mortality adjusted for oesophagogastric surgery (O-POSSUM).

Methods

Data on patients who underwent potentially curative oesophagectomy in a tertiary referral centre for adenocarcinoma or squamous cell carcinoma of the oesophagus were analysed. The in-hospital mortality predicted by O-POSSUM was compared with the actual value by linear analysis.

Results

Twenty-four (3Β·6 per cent) of 663 patients died in hospital. The observed : predicted ratio for in-hospital mortality was 0Β·29. The model had a poor fit (P < 0Β·001). The area under the receiver–operator characteristic curve was 0Β·60 (95 per cent confidence interval 0Β·47 to 0Β·72); P = 0Β·113). O-POSSUM score was not related to the severity of complications.

Conclusion

O-POSSUM overpredicted in-hospital mortality threefold and could not identify patients at higher risk of death. O-POSSUM needs substantial modification before it can be used for comparison of treatment outcomes between centres.


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