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Evaluation of [O-methyl-11C]fluvoxamine as a tracer for serotonin re-uptake sites

✍ Scribed by P Wollmer; R.M Moresco; P Simonelli; M Matarrese; M Rigamonti; G Ortu; R LaGaetana; D Soloviev; M Galli; F Fazio

Book ID
117688467
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
250 KB
Volume
27
Category
Article
ISSN
0969-8051

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The radiosynthesis of nca [O-methyl-11C]
The radiosynthesis of nca [O-methyl-11C]viqualine, through an N-trityl-protected intermediate, as a potential pet radioligand for 5HT re-uptake sites
✍ Claudio Pascali; Victor W. Pike; David R. Turton 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 585 KB

## Abstract Viqualine, {4‐[3‐[3(__R__)‐ethenyl‐4(__R__)‐piperidinyl]propyl]‐6‐methoxyquinoline}, has been labelled in the __O__‐methyl position with no‐carrier‐added (nca) carbon‐11 (__t__~1/2~ = 20.4 min; β^+^ = 99.8%) to provide a potential radioligand for PET studies of 5HT re‐uptake sites. Dire