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Evaluation of nigrostriatal damage and its change over weeks in a rat model of Parkinson's disease: small animal positron emission tomography studies with [11C]β-CFT

✍ Scribed by Limin Liu; Yong Wang; Bo Li; Jun Jia; Zuoli Sun; Jinming Zhang; Jiahe Tian; Xiaomin Wang


Book ID
116799352
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
607 KB
Volume
36
Category
Article
ISSN
0969-8051

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## Abstract We used [^11^C]raclopride (RACLO) and positron emission tomography (PET) to study longitudinally striatal dopamine D~2~ receptor binding in nine patients with Parkinson's disease (PD) at an early drug‐naive stage and 3–5 years later, when motor fluctuations had appeared in seven of them