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Evaluation of new antiemetic agents and definition of antineoplastic agent emetogenicity—state of the art

✍ Scribed by Steven M. Grunberg; David Warr; Richard J. Gralla; Bernardo L. Rapoport; Paul J. Hesketh; Karin Jordan; Birgitte T. Espersen


Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
95 KB
Volume
19
Category
Article
ISSN
0941-4355

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Ametantrone acetate (anthracenedione diacetate, NSC 2875 13) is an experimental antineoplastic agent with activity against a comprehensive panel of solid transplantable tumors in mice. The studies reported here were aimed at establishing the toxicologic profile of this drug. Studies in mice and dogs