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Evaluation of N -Methylpyrrolidone and Its Oxidative Products Toxicity Utilizing the Microtox Assay

โœ Scribed by Campbell, Harry L.; Striebig, Bradley A.

Book ID
121399001
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
113 KB
Volume
33
Category
Article
ISSN
0013-936X

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## Abstract Subcutaneous administration of the LD~50~ dose of methyl isocyanate (MIC) to rats induced severe hyperglycaemia, lactic acidosis and uraemia in rats. Neither methylamine (MA) nor N,Nโ€ฒโ€dimethylurea (DMU), the hydrolysis products of MIC, administered in equimolar doses had any influence o