Evaluation of muscle metabolic activity in the lower limb of a transfemoral amputee using a prosthesis by using 18F-FDG PET imaging––an application of PET imaging to rehabilitation
✍ Scribed by Tetsuya Shinozaki; Keiko Suzuki; Takehiko Yamaji; Akihiro Ichikawa; Tomio Inoue; Kenji Takagishi; Keigo Endo
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 563 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0736-0266
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✦ Synopsis
Abstract
This study used FDG PET to evaluate the lower limb muscles metabolic activities of transfemoral amputees during walking with prostheses. As a preliminary study, FDG PET was applied for two normal adult volunteers to evaluate muscle activity in the lower extremities after gait exercise. This same method was applied for two amputee volunteers with prostheses. We found that FDG accumulated more in both gluteus medius muscles after gait exercise compared to other muscles in normal adult volunteers. In the skilled amputee volunteer, FDG uptake increased in the adductor and gluteus medius in the amputated side, while in the unskilled the adductor, gluteus maximus, and gluteus medius showed increased FDG uptake only in the normal side. This result suggests that basic metabolic changes such as an increase in oxidative metabolism and less reliance on glycolytic activity would occur as a result of skeletal muscle training in amputees. © 2003 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved.