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Evaluation of molecular markers of renal toxicity caused by proximal tubule segment-specific nephrotoxicants in a time-course study

✍ Scribed by Arianna Chiusolo; Rossella Defazio; Alessandro Casartelli; N. Mori; Patrizia Cristofori; Michele Mongillo; Edoardo Zanetti; Andrea Trevisan

Book ID: 119380501
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 91 KB
Volume: 180
Category: Article
ISSN: 0378-4274
DOI: 10.1016/j.toxlet.2008.06.643

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Little is known concerning the sensitivity of aged rats to xenobiotics inducing kidney damage. To increase this knowledge, the age-dependent response of the kidney to hexachloro-1 : 3-butadiene (HCBD) or potassium dichromate (chromate) was investigated. Rats were treated at different ages with a sin