Evaluation of hydroxypropyl methylcellul
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Amol S. Matharu; Michael G. Motto; Mahendra R. Patel; Anthony P. Simonelli; Rute
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Article
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2011
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John Wiley and Sons
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English
⚖ 624 KB
Utilizing gastro-retentive drug delivery systems (GRDDS) to increase absorption of weakly basic drugs by extending their transit time is a promising approach. Swellable systems were evaluated for this purpose. Such systems demonstrate dual mechanism of release-diffusion and erosion. GRDDS requires m