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Evaluation of in vitro tests to assess the efficacy of formulations as topical skin protectants against organophosphorus compounds

โœ Scribed by J. Millerioux; C. Cruz; A. Bazire; V. Polly; G. Lallement; L. Lefeuvre; D. Josse


Book ID
116919911
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
438 KB
Volume
23
Category
Article
ISSN
0887-2333

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A procedure was developed for the in vivo evaluation of the bioavailability of topical formulations containing a limited amount of the active drug product estimated as the rate and extent to which the drug i s released from the vehicle to the skin. It i s assumed that drug transfer follows Fick's la