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Evaluation of human recombinant bone morphogenetic protein-2-loaded tricalcium phosphate implants in rabbits’ bone defects

✍ Scribed by Ph Laffargue; H.F Hildebrand; M Rtaimate; P Frayssinet; J.P Amoureux; X Marchandise


Book ID
117808913
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
126 KB
Volume
25
Category
Article
ISSN
8756-3282

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Restoration of segmental bone defects in
✍ Mori, Masahiro ;Isobe, Masatsugu ;Yamazaki, Yasuharu ;Ishihara, Kazuhiko ;Nakaba 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 517 KB

Recombinant human bone morphogenetic protein-2 (rhBMP-2) was encapsulated in biodegradable poly(DL-lactide-co-glycolide) (PLGA) capsules to regenerate bone by controlling the release rate of rhBMP-2. The rhBMP-2/PLGA capsules containing 12 g of rhBMP-2 were implanted in seven 15-mm segmental defects