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Evaluation of hepatotoxicity of chemicals using hepatic progenitor and hepatocyte-like cells derived from mouse embryonic stem cells

✍ Scribed by Kang, Seok-Jin; Jeong, Sang-Hee; Kim, Eun-Joo; Cho, Joon-Hyoung; Park, Young-Il; Park, Sung-Won; Shin, Hyo-Sook; Son, Seong-Wan; Kang, Hwan-Goo

Book ID
120335675
Publisher
Springer
Year
2012
Tongue
English
Weight
666 KB
Volume
29
Category
Article
ISSN
0742-2091

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## Abstract Recently it was shown that embryonic stem (ES) cells could differentiate into hepatocytes both in vitro and in vivo, however, prospective hepatic progenitor cells have not yet been isolated and characterized from ES cells. Here we presented a novel 4‐step procedure for the differentiati