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Evaluation of hepatic lesions and hepatic parenchyma using diffusion-weighted echo-planar MR with three values of gradient b-factor

✍ Scribed by Takao Moteki; Hiroyuki Horikoshi


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
254 KB
Volume
24
Category
Article
ISSN
1053-1807

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✦ Synopsis


Abstract

Purpose

To determine whether diffusion‐weighted echo‐planar (EP) MR images with very small, small, and large gradient b‐factors are useful in evaluating hepatic lesions and hepatic parenchyma.

Materials and Methods

Approximate values of the apparent diffusion coefficients for diffusion (D) and for flowing spins (D*) for 96 hepatic lesions (26 hepatocellular carcinomas [HCCs], 28 metastases, 26 hemangiomas, and 16 cysts) and the non‐lesion‐bearing regions of parenchyma in 78 livers (50 noncirrhotic and 28 cirrhotic) were calculated from EP images (modified for gradient b‐factors of 3, 50, and 300 second/mm^2^).

Results

Liver cysts and noncirrhotic livers showed statistically higher mean D* values than HCCs, hemangiomas, metastases, and cirrhotic livers (P < 0.05 on Scheffé post hoc analysis). Liver cysts showed statistically higher mean D values than HCCs, metastases, noncirrhotic livers, and cirrhotic livers (P < 0.05). Liver hemangiomas showed statistically higher mean D values than HCCs, noncirrhotic livers, and cirrhotic livers (P < 0.05).

Conclusion

The D* value in addition to the D value may be useful for evaluating the nature of diffusion and flowing spins in hepatic lesions and hepatic parenchyma. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.