Evaluation of gastrointestinal behaviour in the rat of amphiphilic β-cyclodextrin nanocapsules, loaded with indomethacin

Amphiphilic β-cyclodextrins modified on

Amphiphilic β-cyclodextrins modified on the primary face: Synthesis, characterization, and evaluation of their potential as novel excipients in the preparation of nanocapsules

✍ Erem Memişoğlu; Amélie Bochot; Murat Şen; Daniel Charon; Dominique Duchêne; A. A 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 226 KB

The purpose of this study was to synthesize and characterize amphiphilic b-cyclodextrins modi®ed on the primary face with substituents of varying chain lengths (C6 and C14) and bond types (ester or amide). We also aimed to evaluate the potentiality of the new amphiphilic b-cyclodextrins as excipient