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Evaluation of floating and sticking extended release delivery systems: an unconventional dissolution test

✍ Scribed by Thomas Dürig; Reza Fassihi

Book ID
114160631
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
244 KB
Volume
67
Category
Article
ISSN
0168-3659

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The objective of this work was to develop and evaluate a floating-pulsatile drug delivery system intended for chronopharmacotherapy. Floating-pulsatile concept was applied to increase the gastric residence of the dosage form having lag phase followed by a burst release. To overcome limitations of va